双侧颞叶病变的MRI临床诊断.pdf

The British Journal of Radiology, 85 (2012), e782–e792 REVIEW ARTICLE Clinico-radiological spectrum of bilateral temporal lobe hyperintensity: a retrospective review J SUREKA, MD, FRCR and R K JAKKANI, MD, FRCR Department of Radiology, Christian Medical College and Hospital, Vellore, Tamilnadu, India ABSTRACT. Bilateral temporal lobe hyperintensity (BTH) is a commonly encountered MRI finding in a wide spectrum of clinical conditions and often poses a diagnostic challenge to the radiologist. The purpose of this paper is to elucidate several diseases that manifest as BTH on MRI, based on a retrospective review of cranial MRI of 65 cases seen in our institution between October 2007 and September 2010. We found BTH in different clinical scenarios that included infective diseases (herpes simplex virus, congenital cytomegalovirus infection), epileptic syndrome (mesial temporal sclerosis), neurodegenerative disorders (Alzheimer’s disease, frontotemporal dementia, Type 1 myotonic dystrophy), neoplastic conditions (gliomatosis cerebri), metabolic disorders (mitochondrial encephalopathy, lactic acidosis and stroke-like episodes, Wilson’s disease, hyperammonemia), dysmyelinating disease (megalencephalic leukoencephalopathy Received 15 June 2011 with subcortical cysts), and vascular (cerebral autosomal dominant arteriopathy with Revised 6 October 2011 subcortical infarcts and leukoencephalopathy) and paraneoplastic (limbic encephalitis) Accepted 24 October 2011 disorders. The conventional MRI findings with advanced MRI such as diffusion-weighted imaging, susceptibility-weighted imaging and MR spectroscopy along with laboratory DOI: 10.1259/bjr results are potentially helpful in distinguishing the different clinical conditions and thus ’ 2012 The British Institute of