文档详情

sp1- and krüppel-like transcription factorssp1和kruppel-like转录因子.pdf

发布：2017-09-09约10.47万字共8页下载文档

文本预览下载声明

Protein family review Sp1- and Krüppel-like transcription factors c o † ‡ †§ m Joanna Kaczynski* , Tiffany Cook and Raul Urrutia* m e n t Addresses: *Gastroenterology Research Unit, †Tumor Biology Program, and §Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55901, USA. ‡Department of Biology, New York University, New York, NY 10003, USA. Correspondence: Raul Urrutia. E-mail: urrutia.raul@ r Published: 3 February 2003 e v

显示全部

相似文档

sp1／krüppel样转录因子家族研究进展.pdf PO Box 2345 Beijing 100023, China World Chin J Digestol 2004 July;12(7):1641-1645 Fax: +86-10 世界华人消化杂志 ISSN 1009-3079 CN 14-1260/R Email: wcjd@ 2004年版权归世界胃肠病学杂志社
2018-06-06 约2.65万字 5页立即下载
zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages斑马鱼kruppel-like 4因素压制肠道细胞增殖和促进肠道细胞谱系分化.pdf ¨ Zebrafish Kruppel-Like Factor 4a Represses Intestinal Cell Proliferation and Promotes Differentiation of Intestinal Cell Lineages 1 3 2 2 2
2017-09-12 约8.71万字 14页立即下载
tfcat the curated catalog of mouse and human transcription factorstfcat老鼠和人类转录因子的策划目录.pdf Volume 10, Issue 3, Article R29et al.Fulton2009 Open Access Software TFCat: the curated catalog of mouse and human transcription factors *
2017-09-12 约11.12万字 14页立即下载
胃肠道富集Krüppel样因子在胃癌中的表达及意义的中期报告.docx 胃肠道富集Krüppel样因子在胃癌中的表达及意义的中期报告胃癌是全球范围内最常见的恶性肿瘤之一，其发病率和死亡率居高不下。Krüppel样因子（Krüppel-like factors，KLFs）是一组DNA结合转录因子，已被证明在多种生物学过程和疾病中发挥重要作用。一些研究表明，在胃癌中，某些KLFs的表达水平异常高或异常低。然而，对于大多数KLFs在胃癌中的表达及作用尚不清楚。为了研究KLFs在胃癌中的表达及其意义，我们通过实时荧光定量PCR、免疫印迹等方法分析了正常胃黏膜和胃癌组织中KLFs的表达水平。初步结果显示，多个KLFs在胃癌组织中的表达水平明显不同于正常胃黏膜组织，其中一
2023-10-16 约小于1千字 1页立即下载
Krüppel样因子4（KLF4）对人胃癌细胞株SGC-7901生长增殖影响及机制研究.docx Krüppel样因子4（KLF4）对人胃癌细胞株SGC-7901生长增殖影响及机制研究一、引言 1.1研究背景肿瘤作为全球性的严重公共卫生问题，严重威胁着人类的健康与生命。在美国，每年有四分之一的死亡由恶性肿瘤导致。而胃癌作为最常见的上皮源性恶性肿瘤之一，也是主要的肿瘤致死性相关疾病，全球每年约12％的肿瘤患者死于胃癌，其在所有消化系统恶性肿瘤的发病率和死亡率中均位居第二位，对人类健康构成极大威胁。胃癌细胞的迅速生长会引发一系列严重并发症，如消化道梗阻、出血、穿孔等。即便患者接受了胃癌根治术，并进行严格、系统的辅助化疗等治疗，仍面临着高复发率和转移率的问题，癌细胞可发生全身转移，直
2025-05-15 约1.4万字 11页立即下载
temporal and spatial patterning of an organ by a single transcription factor时间和空间模式的器官由一个转录因子.pdf Minireview Temporal and spatial patterning of an organ by a single c
2017-10-31 约5.56万字 4页立即下载
the atonal proneural transcription factor links differentiation and tumor formation in drosophila无调性的颈板转录因子在果蝇链接分化和肿瘤的形成.pdf PLoS BIOLOGY The Atonal Proneural Transcription Factor Links Differentiation and Tumor Formation in Drosophila Wouter Bossuyt1,2,3, Natalie De Geest1,2, Ste
2017-09-07 约5.75万字 10页立即下载
SP1转录因子在小鼠胚胎发育中的调控机制研究.docx SP1转录因子在小鼠胚胎发育中的调控机制研究目录一、内容简述．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．4 研究背景及意义．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．4 1.1转录因子在生物学中的作用概述．．．．．．．．．．．．．．．．．．．．．．．．．．．6 1.2SP1转录因子的生物学地位和重要性．．．．．．．．．．．．．．．．．．．．．．．．8 研究目的与主要问题．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．．9 2.1研究目的．．．．．．．．．．．．．．．．．．．．．
2025-04-26 约5.08万字 81页立即下载
the ap-2 family of transcription factorsap-2家族转录因子.pdf Protein family review The AP-2 family of transcription factors c
2017-09-12 约10.13万字 8页立即下载
conserved and distinct modes of crebatf transcription factor regulation by pp2ab56γ and genotoxic stress守恒和不同模式由pp2ab56γcrebatf转录因子调控,基因毒性压力.pdf Conserved and Distinct Modes of CREB/ATF Transcription Factor Regulation by PP2A/B56c and Genotoxic Stress Naval P. Shanware, Lihong Zhan, John A. Hutchinson, Sang Hwa Kim, Leah M. Williams, Randal S. Tibbetts* Department of Pharmacology, Program in Molecular and Cellular Pharmacology and Molec
2017-09-09 约6.19万字 10页立即下载
start lipidsterol-binding domains are amplified in plants and are predominantly associated with homeodomain transcription factors开始在植物和lipidsterol-binding域放大主要是与homeodomain转录因子有关.pdf Volume 5, Issue 6, Article R41et al.Schrick2004 Open Access Research START lipid/sterol-binding domains are amplified in plants and are
2017-09-08 约字 16页立即下载
strand transfer and elongation of hiv-1 reverse transcription is facilitated by cell factors in vitro链转移和伸长,推动了hiv - 1逆转录的体外细胞因子.pdf Strand Transfer and Elongation of HIV-1 Reverse Transcription Is Facilitated by Cell Factors In Vitro David Warrilow1,2, Kylie Warren1,3, David Harrich1,2* 1 Division of Immunology and Infectious Disease, Queensland Institute of Medical Research, Brisbane, Australia, 2 Griffith Medical Research
2017-09-08 约6.58万字 9页立即下载
the homeodomain-containing transcription factors arx and pax4 control enteroendocrine subtype specification in micehomeodomain-containing转录因子arx和pax4控制enteroendocrine亚型规范在老鼠身上.pdf The Homeodomain-Containing Transcription Factors Arx and Pax4 Control Enteroendocrine Subtype Specification in Mice 1 2,3 1 2,3 1 Anthony Beucher , Elisab
2017-09-11 约7.22万字 11页立即下载
biochemical characterization of diverse stat5b-binding enhancers that mediate growth hormone-activated insulin-like growth factor-i gene transcription生化特征的多样化stat5b-binding增强剂,调解增长hormone-activated胰岛素样生长因子基因转录.pdf Biochemical Characterization of Diverse Stat5b-Binding Enhancers That Mediate Growth Hormone-Activated Insulin-Like Growth Factor-I Gene Transcription 1 1 1 2 1 Ben Varco
2017-08-26 约6.84万字 11页立即下载
common snps in myelin transcription factor 1-like (myt1l) association with major depressive disorder in the chinese han population常见的单核苷酸多态性髓转录因子1(myt1l)与重度抑郁症在中国汉族人群.pdf Common SNPs in Myelin Transcription Factor 1-Like (MYT1L): Association with Major Depressive Disorder in the Chinese Han Population 1,2 1 1 1 1 2 2 2 1 Ti W
2017-11-17 约3.47万字 5页立即下载