connectivity of default-mode network is associated with cerebral edema in hepatic encephalopathy静息状态网络的连通性与脑水肿在肝性脑病.pdf

Connectivity of Default-Mode Network Is Associated with Cerebral Edema in Hepatic Encephalopathy 1,2 2,3 4 5 6 Wei-Che Lin , Tun-Wei Hsu , Chao-Long Chen , Changwei W. Wu , Cheng-Hsien Lu , Hsiu- 1,2 7 8,9 1 . 2,10 . Ling Chen , Shau-Hsuan Li , Pin-Yang Yeh , Yu-Fan Cheng * , Ching-Po Lin * 1 Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, 2 Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei, Taiwan, 3 Department of Diagnostic Radiology, Taipei Veterans General Hospital, Taipei, Taiwan, 4 Department of Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, 5 Institute of Biomedical Engineering, National Central University, Taoyuan, Taiwan, 6 Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, 7 Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan, 8 Instiute of Allied Health Science, College of Medicine, National Cheng Kung University, Tainan, Taiwan, 9 Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung, Taiwan, 10 Lab for Brain Connectivity, Institute of Neuroscience, National Yang-Ming University, Taipei, Taiwan Abstract Cerebral edema, a well-known feature of acute liver disease, can occur in cirrhotic patients regardless of hepatic encephalopathy (HE) and adversely affect prognosis. This study characterized a