3药物洗脱支架与裸支架置入治疗冠心病的安全性及生物相容性比较.pdf

中国组织工程研究与临床康复 第12 卷 第13 期 2008 –03 –25 出版 Journal of Clinical Rehabilitative Tissue Engineering Research March 25, 2008 Vol.12, No.13 综 述 药物洗脱支架与裸支架置入治疗冠心病的安全性及生物相容性比较 1 2 胡延春 ，钱久光 Safety and biocompatibility of drug-eluting stent versus bare metal stent in treating coronary artery disease 1 2 Hu Yan-chun , Qian Jiu-guang Abstract: The most improvement of drug-eluting stent compared with bare metal stent is that there are drug vector and drug in the 1Department of drug-eluting stent. The drug vector of drug-eluting stent is coated with polymer, which can deliver sufficient drug, and control drug Radiology, 2Department of decomposition, dispersion, and release after the stent is implanted into human body. In clinical treatment, the biocompatibility and Cardiology, First integrity of polymer coated vector can influence safety of drug-eluting stent, and drug release control can influence the efficacy of Hospital of Qiqihar the stent. The coated drug should have the capability to protect endothelium, and keep stent smooth to improve stent biocompatibility. Medical University, Qiqihar 161041, Scaffold materials with scientific absorbable and drug release system of polymer coated vector are developing trend of future China drug-eluting stent. Hu Yan-chun, Asso- ciate chief physician, Hu YC, Qian JG.Safety and biocompatibility of drug-eluting stent