中山大学2003至2004学年-第一学期细胞生物学期中考试试题.doc

中山大学2003至2004学年第一学期细胞生物学期中考试试题 中山大学生科院 细胞生物学期中试卷 (2001级生物科学、生物技术专业、进修教师、交换生,140人) 任课教师∶ 王金发 2003年11月22日 姓??名∶???????????????专??业∶???????????? ??? 一 二 三 四 五 六 七 总????分 ? 一、填空题(每空0.5分，共5分) 1.??决定红细胞ABO血型的物质是糖脂，它由脂肪酸和寡糖素链组成。A型血糖脂上的寡糖链较O型多一个??????????????????????????；B型血仅多一个???????????????。 2.??根据题意,?将与A、B、C、D相对应的词用连线连起来: Cells communicate in ways that are analogous to human communication. Decide which of the following forms of human communication are analogous to autocrine, paracrine, endocrine, and synaptic signaling by cells. ????A. A telephone conversation:????????????????????autocrine ????B. Talking to people at a cocktail party:????????endocrine ????C. A radio announcement:?????????????????????????synaptic signaling ????D. Talking to yourself :?????????????????????????paracrine 3.????????????????????What is the major factor that determines the limit of resolution of a light microscope? 4.??编码载脂蛋白B的基因在肠组织中转录成mRNA后,第2153位的C被????????形成U,使CAA密码转变成终止密码UAA,?使翻译提前终止。 5.????????????是细胞外基质的受体蛋白。在结构上，它们是异二聚体，。这种跨膜蛋白的细胞外部分有一个球形的头部，可与细胞外基质蛋白结合，而细胞质结构域则可与????????????????????相结合。 二、判断以下各题是否正确,?若正确,?用T表示,?不正确用F表示,并做简要说明。?(每题1分，共10分) 1.??Both the GTP-bound?a?subunits and nucleotide-free?b??complexes, but not GDP-bound, fully assembled G proteins, activate other molecules downstream of G-protein-linked receptors.??? 答: 2.??The density of water is less than the density of ice. 答: 3.??Water has a high specific heat. 答: 4.??There is no fundamental distinction between signaling molecules that bind to cell-surface receptors and those that bind to intracellular receptors. 答: 5.??How is it that different cells can respond in different ways to exactly the same signaling molecule even when they have identical receptors? 答: 6.??Protein kinase A itself is different in different cell types, which explains why the effects of cyclic AMP vary depending on the target cell. 答: 7.??It is thought that extracellular ligand binding to a receptor tyrosine kinase activates the intracellular catalytic d