【2017年整理】05生物氧化.ppt

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * 磷酸化合物水解的标准自由能变 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ATP Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ATP + H2O ADP + Pi ΔG0’=-30.5 KJ/mol ADP + H2O AMP + Pi ΔG0’=-30.5 KJ/mol AMP + H2O 腺苷+ Pi ΔG0’=-14.2 KJ/mol Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ATP在能量转运中的地位和作用 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ATP在磷酸基团转移中所起到的中间传递体的作用，可以说是一个转移磷酸基团“共同中间传递体”，它是能量的携带者和转运者。 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ATP的作用 作为能量载体，提供合成代谢或分解代谢初始阶段所需的能量； 供给机体生命活动所需的能量； 生成核苷三磷酸（NTP）； 将高能磷酸键转移给肌酸以磷酸肌酸（creatine phosphate）形式储存 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 将高能磷酸键转移给肌酸以磷酸肌酸形式储存 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. ATP的生成方式 氧化磷酸化：代谢物脱下的氢经电子传递链与氧结合成水的同时，逐步释放出能量，使ADP磷酸化为ATP的过程 底物水平磷酸化：代谢物脱氢与ADP（或GDP）的磷酸化相偶联 底物水平磷酸化共3个反应 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 底物水平磷酸化 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 线粒体的结构 四、氧化磷酸化作用 是需氧细胞生命活动的基础，是主要的能量来源 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 线粒体结构 线粒体结构模式图 线粒体嵴的分子组成 Evaluation only. Created with Aspose.Slides for .NET 3.5 Client Profile 5.2.0.0. Copyright 2004-2011 Aspose Pty Ltd. 1、氧化磷酸化的概念 是与电子传递过程偶联的磷酸化过程 伴随电子从底物到O2的传递，ADP被磷酸化生成ATP的酶促过程，这种 氧化与磷酸化相偶联的作用称为氧化磷酸化 这是需氧生物合成AT