生物涂层制备技术的研究现状及进展.pdf
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第42 卷 第5 期 Vol.42 No.5
20 12 年5 月 Electric Welding Machine May 20 12
生物涂层制备技术的研究现状及进展
胡淑慧,黄安国,刘 源,李志远
(华中科技大学 材料科学与工程学院,湖北 武汉430074)
羟基磷灰石(HA) 由于具有良好的生物相容性和骨组织诱导性,被认为是替代人体硬组织的一
摘要:
种很好的生物医用材料,但其溶解度较高,降低植入体的长效性,而将氟渗入HA 晶格中能提高HA
结构稳定性并降低其溶解性,将硅掺入HA 晶格中能有效地提高HA 的生物活性,因此含氟羟基磷灰
石(FHA)和含硅羟基磷灰石(Si-HA)成为了新兴的改性材料。介绍了羟基磷灰石(HA)、含氟羟基磷灰石(FHA)
以及含硅羟基磷灰石(Si-HA) 的性能特点以及涂层的制备技术,重点阐述了采用激光熔覆技术制备生
物涂层的研究现状以及本课题组的研究进展,指出了目前研究中存在的不足,并展望了生物涂层今后
的研究和发展趋势。
羟基磷灰石(HA);含氟羟基磷灰石(FHA);含硅羟基磷灰石(Si-HA);激光熔覆
关键词:
TG456.7 C 1001-2303(2012)05-0062-05
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Research status and progress of bioceramic coating preparation technology
HU Shu-hui,HUANG An-guo,LIU Yuan ,LI Zhi-yuan
(College of Materials Science and Engineering,Huazhong University of Science and Technology,Wuhan 430074,China)
:
Abstract Hydroxyapatite(HA)coating is considered as a good type of biomedical material for replacing hard tissues of human body due
to its excellent biocompatibility and osteoinduction, but its higher solubility decreases the long-term performance of implants. Fluorine
can be incorporated into HA crystal structure by substituting OH-groups with F-ions to form fluoridated hydroxyapatite(FHA) ,FHA
possesses lower solubility and higher structure stability than pure HA while maintaining the comparable bioactivity and biocompatibility.
The addition of Si in HA leads to an improvement of the bioactivity and enhancement of bone growth. Thus fluoridated hydroxyapatite
(FHA)and Si -substituted hydroxyapatite (Si -HA)become the developing modified materials.In the present work ,the performance
characteristics and fabri
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