免疫學读书笔记.docx

中文：禽流感新型疫苗研究进展作者：?刘志刚；?刘立峰；?陈伦勇；?孙青松；?金梅林；关键词：?禽流感；?新型疫苗；?研究进展内容：禽流感(AI)是由A型流感病毒引起的多种禽类及鸟类表现为轻度呼吸道症状或急性败血症为特征的传染病。该病不仅对我国禽类养殖业造成巨大的经济损失,而且还具有重要的公共卫生学意义。目前用于控制禽流感的最有效手段仍然是疫苗接种,论文就有关禽流感预防的重组活载体疫苗、基因工程亚单位疫苗、DNA疫苗、禽流感表位疫苗等新型疫苗进行简要综述,旨在为禽流感的防控提供参考。?English: Willingness to receive a hypothetical avian influenza vaccine among US military personnel in mid-deployment.Author:Porter Chad K?,??Fitamaurice Gina?,??Tribble David R?,??Armstrong Adam W?,?Mostafa Manal?,??Riddle Mark SContent:Though no avian influenza vaccine currently exists, development efforts have increased. Given recent reports of suboptimal vaccination rates among US military personnel, we sought to assess factors associated with a willingness to receive a hypothetical avian influenza vaccine. A self-administered questionnaire was completed by US military personnel during mid-deployment to Iraq, Afghanistan, and surrounding regions. Respondents were predominately male (86.2%), Army (72.1%), and enlisted (86.3%) with a mean age of 29.6 y. The majority (77.1%) agreed to receive an avian influenza vaccine if available. Exploratory factor analysis (EFA) identified two factors, vaccine importance and disease risk, that best described the individual perceptions and both were associated with an increased willing?ness to receive the hypothetical vaccine (OR: 8.2 and 1.6, respectively). Importantly, after controlling for these factors differences in the willingness to receive this hypothetical vaccine were observed across gender and branch of service. These results indicated that targeted education on vaccine safety and efficacy as well as disease risk may modify vaccination patterns in this population.influenza　列性感冒vaccine　菌苗中文:经皮肺穿刺对确定无反应性肺炎病原体的临床分析作者：钱麒钰关键词：?经皮肺穿刺；?无反应性肺炎；?病原体；?涂片内容：背景和目的无反应性肺炎(Nonresponding pneumonia)是近几年提出的临床概念,指在接受抗感染治疗的情况下,社区获得性肺炎(Community-acquired pneumonia,CAP)患者没有获得显著改善的一种临床情况,临床上并不少见,但是目前尚缺乏统一的诊断标准。据流行病学统计,CAP患者中有部分患者对于最初的经验性抗感染治疗无效,继而发展为无反应性肺炎或进展性肺炎,且病死率呈逐年上升趋势。而无反应性肺炎的病死率为CAP的数倍,故越来越受到临床医