a 3-year randomized trial of lifestyle intervention for cardiovascular risk reduction in the primary care setting the swedish bj？rkn？s study三年生活方式干预的随机试验对心血管风险降低在初级保健设置瑞典bj rkn研究.pdf

A 3-Year Randomized Trial of Lifestyle Intervention for Cardiovascular Risk Reduction in the Primary Care ¨ ¨ Setting: The Swedish Bjorknas Study 1,2 3 3,4 Margareta K. Eriksson *, Paul W. Franks , Mats Eliasson ¨ ¨ ˚ ˚ 1 Bjorknas Primary Health Care Centre, Boden, Sweden, 2 Department of Community Medicine and Rehabilitation, Umea University, Umea, Sweden, 3 Department of ˚ ˚ ˚ Public Health and Clinical Medicine, Umea University, Umea, Sweden, 4 Department of Medicine, Sunderby Hospital, Lulea, Sweden Abstract Background: Successfully transferring the findings of expensive and tightly controlled programmes of intensive lifestyle modification to the primary care setting is necessary if such knowledge is to be of clinical utility. The objective of this study was to test whether intensive lifestyle modification, shown previously in tightly-controlled clinical trials to be efficacious for diabetes risk-reduction among high-risk individuals, can reduce cardiovascular risk factor levels in the primary care setting. ¨ ¨ Methodology / Principal Findings: The Swedish Bjo rknas study was a randomized controlled trial conducted from 2003 to 2006 with follow-up on cardiovascular risk factors at 3, 12, 24 and 36 months. A total of 151 middle-aged men and women at moderate- to high-risk of cardiovascular disease from northern Swed