adherence to prescribed oral medication in adult patients undergoing chronic hemodialysis a critical review of the literature遵守规定的口服药物治疗成人慢性血液透析患者接受一个关键文献之回顾.pdf

May 14, 2009 EUROP AN J OURNAL OF M DICAL RESEARCH 185 ur J Med Res (2009) 14: 185-190 © I. Holzapfel Publishers 2009 ADHERENC TO PRESCRIBED ORAL MEDICATION IN ADULT PATIENTS UNDERGOING CHRONIC HEMODIALYSIS: A CRITICAL REVIEW OF TH LITERATUR 1 2 1 H. Schmid , B. Hartmann , H. Schiffl 1KFH Nierenzentrum Muenchen Laim, Munich, Germany, 2Department of Nephrology, Medical Clinic I, University Hospital Munich-Grosshadern, Munich, Germany Abstract serves as a substitute for all renal functions. RRT un- Objective: Poor adherence to complex multimodal doubtedly contributes to long-term survival. However, therapies is a widely recognized problem in the daily morbidity and mortality of maintenance dialysis pa- care of dialysis patients, contributing to excess mor- tients remain high: only about one third of the US he- bidity and mortality of this population. While a few modialysis (HD) patients are alive after 5 years [2]. studies have been devoted to understanding patient Cardiovascular diseases are the leading cause of death nonadherence, their results were somewhat controver- in SRD patients [3]. Notably, patients with ESRD sial. The goals of this review are to quantify nonad- have a very high prevalence of cardiovascular disease herence to certain oral medications, to raise awareness risk