04356夏晓波湘雅医院眼科.pdf
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中南大学学报(医学版)
2009,34(4) http://xbyx.xysm.net
356 JCentSouthUniv(MedSci)
微穿透性小梁切除术联合羊膜植入治疗
开角型青光眼的中远期疗效
江海波,夏晓波,邓琪琳,王平宝
(中南大学湘雅医院眼科,长沙410008)
[摘要] 目的:研究微穿透性小梁切除术联合羊膜植入术治疗开角型青光眼的中远期疗效及其并
发症。方法:对30例(49只眼)开角型青光眼患者行微穿透性小梁切除术联合羊膜植入术,观察术前和
术后视力、眼压、视野、滤过泡,并进行统计学分析。结果:随访 6~24(15.93±2.35)月。术前及术后
24月时眼压分别为(36.84±11.02)mmHg和(18.24±1.34)mmHg(P=0.000),术前及术后使用的抗
青光眼药物分别为(2.76±0.69)种和(0.59±0.89)种(P<0.05),早中期视野缺损视野指数较术前
有改善(P<0.05),晚期视野缺损没有改善。术后 24月70.8%形成功能性滤过泡,末次随访时手术完
全成功率75.5%(37/49),质量成功率93.9%(46/49)。手术前后视力比较无统计学差异。无严重并
发症发生。结论:微穿透性小梁切除术联合羊膜植入是治疗开角型青光眼安全有效的方法,中远期疗效
稳定可靠。
[关键词] 青光眼; 开角型; 微穿透性小梁手术; 羊膜
[中图分类号] R775.2 [文献标识码] A [文章编号] 16727347(2009)04035606
Midtermandlongtermclinicaleffectof
microperforatingtrabecularsurgerywithamniotic
membraneimplantsonopenangleglaucoma
JIANGHaibo,XIAXiaobo,DENGQilin,WANGPingbao
(DepartmentofOphthalmology,XiangyaHospital,CentralSouthUniversity,Changsha410008,China)
Abstract: Objective Toevaluatethemidtermandlongtermclinicaleffectandcomplica
tionofmicroperforatingtrabecularsurgery(MPTS)withamnioticmembraneimplantsonopenangle
glaucoma(OAG).Methods ThirtyOAGpatients(49eyes)weretreatedwithMPTSwithamniotic
membraneimplants.Visualacuity,intraocularpressure,visualfield,typeofblebs,andcomplica
tionswererecordedpreandpostoperatively.Results Patientswerefollowedupfor6~24
(15.93±2.35)months.ThemeanIOPsbeforetheoperationand24monthsaftertheoperation
were(36.84±11.02)mmHgand(18.24±1.34)mmHg,respectively(P=0.000).The
meannumbersofantiglaucomadrugsusedbeforeandaftertheoperationwere(2.76±0.69)and
(0.59±0.89),respectively(P<0.05).Theg
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