37例老年患者胰十二指肠切除术手术风险因素探讨(附6例死亡病例分析).pdf

东 南 大 学 学 报 ( 医 学 版 ) 2 　20 07, N ov; 26 (6) : 4 13 4 16 J Sou theastUn iv ( M ed Sci Ed i ) ·4 13 · Ea r th orm f ib r in o lyt ic en zym e en han ce s ra d io sen sit iv ity of h um an e sop ha gea l car c in om a cell l in e ECA 109 1 1 2 3 4 CHEN H on g , HUAN G J in , TU W e n 2yon g , ZHAN G Zh i2guo , CHEN B ao 2a n ( 1. Depa rmt en t of Gastroen tero log y, Zh ongd a Hospita l, Sou th east U n ivers ity, N a njin g 21000 9, Ch ina; 2. D epa rtm en t of Tum or R a dio thera py, the Second Hosp ita l of N a njing, Affil ia ted to th e Schoo l ofM ed icin e, Sou thea st U n iversity, N anjing 210003, Ch in a; 3. Inst itu te of B iochem istry an d Imm uno logy, N a njin g Ag ricu lture U n iversity, N anjing 2 100 95, Ch ina; 4. D epa rtm ent of H em o tology, Zh ongd a Hospital, Sou theast Un iversity, N a njing 210009 , Ch ina ) Ab str a ct :O bj ec t ive　To study the rad io sen sitivity2ench ancing effect o f earth orm fibr ino ly tic enzym e ( E FE ) on h um an esop hageal ca rc inom a ce ll line and its rela ted mechan ism. M eth od s　The e soph agea l carcinoma cell line EC A 109 a s u sed in the exp ermi ent. M TT assay as p erform ed to ana lyze the inh ib itory ra tio of the cell line, the clono gen ic a ssay as u sed to dete rm ine cell su rvival fraction , th e flo cytom ete r as u sed to check cell cycle d istr ibu tion and the