胆囊切开取石在合并胆囊结石的遗传性球形红细胞增多症患儿的可行性研究.pdf

274JournalofHepatobiliar,Aug.2024

肝胆外科杂志2024年8月第32卷第4期

胆囊切开取石在合并胆囊结石的遗传性

球形红细胞增多症患儿的可行性研究

袁俊俊，戚士芹

目的探索加行胆囊切开取石术在行全脾切除术治疗遗传性球型红细胞增多症（Hereditaryspherocytosis，HS）

【摘要】

合并胆囊结石患儿的可行性。方法回顾性分析2019年10月至2022年5月我院收治的15例合并有胆囊结石的HS患儿的

切开取石术，术中用胆道镜取石并确认取尽结石。结果15例患儿均成功手术，术后均恢复顺利。术后7天复查B超：13例

无结石，2例有泥沙样结石，经口服熊去氧胆酸治疗，分别术后3月、6月复查超声结石消失。随访至今，所有患儿未出现再发

对合并有胆囊结石的HS患儿，全脾切除的同时行胆囊切开取石术是可行的。

胆囊结石。结论

【关键词】胆囊切开取石；胆囊结石；遗传性球形红细胞增多症；儿童

【中图分类号】R657.4【文献标识码】A【文章编号】1006-4761(2024)04-0274-04

Feasibilitystudyofcholecystolithotomyinchildrenwithhereditaryspherocytosiscomplicatedwithgallstones(YUANJun-

un,QIShi-qin.TheFifthClinicalSchoolofMedicine,AnhuiChildrensHospital,ChildrensMedicalCenterofAnhuiMedicalUniver-

ity,Hefei230000,China)

[Abstract]ObjectiveToexplorethefeasibilityoflaparoscopicsplenectomycombinedwithcholecystotomyforthetreatmentof

childrenwithhereditaryspherocytosis(HS)andconcurrentgallstones.MethodTheclinicaldataandfollow-upresultsof15children

withHSandgallstonesadmittedtoourhospitalfromOctober2019toMay2022wereretrospectivelyanalyzed.Amongthe15cases,

therewere7malesand8females,agedbetween3-14yearsold(meanage:8.8±3.4years).Allsurgeriesconsistedofsingle-port

laparoscopicsplenectomyfollowedbycholecystotomy,duringwhichgallstoneremovalwasconfirmedusingcholedochoscopy.Results

All15childrenunderwentsuccessfulsurgeryandhadsmoothpostoperativerecovery.Follow-upultrasoundexaminationsconductedat

postoperativedaysevenshowednostonesin13cases,whiletwocaseshadsediment-likestonesthatdisappearedafteroraladministra-

tionofUDCAatthreemonthsandsixmonthspostoperativelyrespectively.Untilnow,noneofthepatientshaveexperience