免疫细胞功能检测在恶性肿瘤患者外周血中的 表达和临床意义.pdf
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Hans Journal of Biomedicine 生物医学, 2017, 7(3), 54-58
Published Online July 2017 in Hans. /journal/hjbm
/10.12677/hjbm.2017.73009
Expression of Immune Cell Function in
Peripheral Blood of Patients with Malignant
Tumor and Its Clinical Significance
1 1 1* 1 2 1 1
Qin Ge , Guodong Xie , Jing Cai , Jizhong Zhao , Jibin Liu , Baixia Yang , Juanjuan Cui ,
Chunxia Chu1
1
Department of Radiotherapy, Tumor Hospital of Nantong, Nantong Jiangsu
2
Biotherapy Center, Tumor Hospital of Nantong, Nantong Jiangsu
nd th th
Received: Jun. 22 , 2017; accepted: Jul. 9 , 2017; published: Jul. 12 , 2017
Abstract
Objective: To investigate the clinical value of immune cell in peripheral blood of patients with ma-
lignant tumor, and to explore its clinical value in the diagnosis and treatment of cancer patients.
Methods: 60 cases of cancer patients, including 20 cases of esophageal cancer, lung cancer in 20
cases, 10 cases of nasopharyngeal carcinoma, other tumors (including laryngeal cancer in 1 case,
tongue cancer in 1 case, breast cancer in 3 cases, 1 case of skin malignant melanoma, rectal cancer
4 cases) and 20 normal control group peripheral blood T lymphocyte subsets percentage, B lym-
phocyte percentage, NK cell percentage, compared with the differences of normal control group.
Results: The percentage of total T lymphocytes CD3+, assisted/induced T lymphocyte CD4+ and
helped inhibited T lymphocyte ratio CD4+/CD8 in peripheral blood of tumor patients was signifi-
cantly lower than that of healthy group (P 0.05). The percentage of inhibition cytotoxicity T
lymphocyte CD8+ was slightly highe
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