the effect of systematic pediatric care on neonatal mortality and hospitalizations of infants born with oral clefts系统儿科护理的影响唇腭裂新生儿死亡率和住院的婴儿出生.pdf
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Wehby et al. BMC Pediatrics 2011, 11:121
/1471-2431/11/121
RESEARCH ARTICLE Open Access
The effect of systematic pediatric care on
neonatal mortality and hospitalizations of infants
born with oral clefts
1 2 3 4 5 6
George L Wehby , Eduardo E Castilla , Norman Goco , Monica Rittler , Viviana Cosentino , Lorette Javois ,
5,7 8 9 10 11
Mark Kindem , Hrishikesh Chakraborty , Graca Dutra , Jorge S López-Camelo , Iêda M Orioli and
Jeffrey C Murray 12*
Abstract
Background: Cleft lip and/or palate (CL/P) increase mortality and morbidity risks for affected infants especially in
less developed countries. This study aimed at assessing the effects of systematic pediatric care on neonatal
mortality and hospitalizations of infants with cleft lip and/or palate (CL/P) in South America.
Methods: The intervention group included live-born infants with isolated or associated CL/P in 47 hospitals
between 2003 and 2005. The control group included live-born infants with CL/P between 2001 and 2002 in the
same hospitals. The intervention group received systematic pediatric care between the 7th and 28th day of life. The
primary outcomes were mortality between the 7th and 28th day of life and hospitalization days in this period
among survivors adjusted for relevant baseline covariates.
Results: There were no significant mortality differences between the intervention and control groups. However,
surviving infants with associated CL/P in the intervention group had fewer hospitalization days by about six days
compared to the associated control group.
Conclusions: Early systematic pediatric care
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