HIFU技术中的超声空化及空化增强效应研究进展.pdf

310 2006 22 2 Chin J M ed Imaging T echn ol , 2006, V ol 22, N o 2 Progress of ultrasonic cavitation and cavitation-induced enhancement effect in high intensity focused ultrasound REN X iao-long , ZH O UX iao-dong * (D ep artment of Ultrasound , X ij ing H osp ital , the Fourth M ilitar M edical Univ ersit , X ian 7 10032, China) [Abstract] U ltr asonic cav itation is o ne of pr edo minant mechanism s in high intensit y focused ultr asound ( H IFU tr eatment . Eff icient ly- induced ultr asonic cav itation can be used to increase the co agulat ed vo lume and enhance the ther apeutic eff iciency of H IFU . Recent studies hav e show n that micro bubble co ntr ast ag ents ar e impo rtant f acto rs in enhancing the therapeut ic ef- f iciency o f H IFU . T hey have po tent ial to act as cav itation nuclei and ar e likely to low er t he tissue damag e thr eshold and cau se a g reater coag ulated vo lume. A long w ith the development of H IFU eff iciency enhancement studies, HIF U w ill be mo re eff ec- t ive and pow erful in clinical tumo r tr eat ment . [Key words] H ig h intensity focused ultraso und; Contrast media, microbubbles; Cav itation ; Imag e enhancement HIFU * 任小龙 综述, 周晓东 审校 ( , 7100 32 [ ] ( HI FU , HIF U HIF U H IFU , , H IFU , H IFU , [ ] ; , ; ; [ ] R44 5. 1 [ ] A [ ] 100 3- 32 89 ( 2006 02- 0310-0 3 , ( high-intensit y focused ult ra- sound, H I FU , 1 H I FU , H IFU 50 , , H IFU , H IFU [ 1] , H IFU 1 , 90 , H I FU 65 , , [ 2 ,