基于斑马鱼模型的中药代谢研究思路与方法_看图王.pdf

中草药　Chinese Traditional and Herbal Drugs　40 7 009 7 ·1009 · · · ＊ 1 1 1 2 韦英杰 ,宁　青 ,贾晓斌 , 龚祝南 (1. , , 　210028; 2., , 　210097) 　:, 。, 。、、 、、, , 。 :;;; :R285.61　　　:A 　　　:0253-2670(2009)07-1009-03 Thoughts and methods for metabolic study of Chinese materia medica based on zebrafish model 1 1 1 2 WEI Ying-jie , NING Qing , JIA Xiao-bin , GONG Zh -nan (1.Key Laboratory of New Dr g Delivery System of Chinese Materia Medica, Key Laboratory of Scientific Preparation for Clinical Effective Prescription of S tate Administration of Traditional Chinese Medicine, Jiangs Province Academy of Chinese Medicine, Nanjing 210028, China;2.Center for New Dr g Research and Development, Jiangs Province Key Laboratory for Molec lar and M edical Biotechnology, College of Life Science, Nanjing Normal University, Nanjing 210097, China) Abstract:Access to domestic and foreign literat res, the stat s and lack of metabolic st dy on Chinese materia medica (CM M )have been overview ed;The basis for establishing the zebrafish metabolic model of CMM has been analyzed;The tho ghts and methods for the establishment of the model have been p t forw ard.T he metabolic model of zebrafish co ld be expected to provide a simple, model, biological, systematic, and efficient new method for CMM metabolic st dy.It is of great significance to enhance the research level of physiological disposition of CM M and to accelerate the modernization process of CM M. Key words:zebrafish;metabolism of Chinese materia medica;tho ght and method;modernization of tradilional Chinese medicine [3,4] [5, 6] 　　, 、 、、