环磷酰胺与雷公藤多甙治疗儿童难治性肾病综合征疗效比较（论文资料）.doc

环磷酰胺与雷公藤多甙治疗儿童难治性肾病综合征疗效比较（论文资料） 文档信息 ： 文档作为关于“医学心理学”中“内科学”的参考范文，为解决如何写好实用应用文、正确编写文案格式、内容素材摘取等相关工作提供支持。正文7394字，doc格式，可编辑。质优实惠，欢迎下载！ 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：环磷酰胺与雷公藤多甙治疗儿童难治性肾病综合征疗效比较 2 1 资料与方法 3 2 结果 4 3 讨论 5 文2：来氟米特与环磷酰胺治疗难治性肾病综合征的疗效比较 6 1临床资料 6 2治疗及观察方法 7 3疗效判定标准 7 参考文摘引言： 9 原创性声明（模板） 11 文章致谢（模板） 11 正文 环磷酰胺与雷公藤多甙治疗儿童难治性肾病综合征疗效比较（论文资料） 文1：环磷酰胺与雷公藤多甙治疗儿童难治性肾病综合征疗效比较 Comparison between the therapeutic effects of cyclophosphamide and tripterygium wilfordii hook on children′s refractory nephrotic syndromeSONG Bing．Department of Pediatrics，Dazhu Country People′s Hospital of Sichuan Province，Dazhu，635100，China【Abstract】 Objective To observe the therapeutic effects，the side-effects and the relapse ratio of cyclophosphamide and tripterygium wilfordii hook on children′s refractory nephrotic syndrome．Methods 55 patients were randomly divided into two groups：the cyclophosphamide(CTX) group with 30 patients and the tripterygium wilfordii hook (TⅡ) group with 25 patients．The CTX patients were given CTX8～12 mg/kg of venous inflow once a day and two days′ treatment was a treatment period which was given every 2～4 weeks，The patients had 6～10 treatment coues with the accumulation of less than 200 mg/kg；The TII patients took orally 1 mg/(kg·d) of TII three times every day with 30 mg per day at the most，The treatment period was three months．All the patients took orally 1 mg/(kg·d) of prednisone three times every day，and 4 weeks later took it once every other day，reducing the medicine amount gradually．The rest of the medicine they took were the same．Results The therapeutic effects of the CTX group were better than those of the TⅡ group(χ2=4．30，P＜0．05 with obvious difference) with fewer side-effects in short term and with lower relapse ratio(χ2=4．86，P＜0．05，obvious difference)．Conclusion The ictus treatment of cyclophosphamide on children′s refractory nephrotic syndromewas fit to be adopted as basic level．【Key words】 Cyclophosphamide；Tri